Phosphatase and Tensin Homolog 抗体
(Phosphatase and Tensin Homolog (PTEN))
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT\\/PKB signaling pathway. [provided by RefSeq, Jul 2008].
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Phosphatase and Tensin Homolog 抗体 by 适用
Find Phosphatase and Tensin Homolog 抗体 for a variety of species such as anti-Human Phosphatase and Tensin Homolog, anti-Mouse Phosphatase and Tensin Homolog, anti-Rat Phosphatase and Tensin Homolog. The species listed below are among those available. Click on a link to go to the corresponding products.
Phosphatase and Tensin Homolog 抗体 by 应用范围
Find Phosphatase and Tensin Homolog 抗体 validated for a specific application such as WB, DB, ELISA, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.
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Find available monoclonal or polyclonal Phosphatase and Tensin Homolog 抗体. Click on a link to go to the corresponding products.
Popular Phosphatase and Tensin Homolog 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (2)
- (4)
Cat. No.
ABIN6242545
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC
Validations
- (7)
Cat. No.
ABIN3032214
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
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- (3)
Cat. No.
ABIN6242539
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC
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- (5)
Cat. No.
ABIN3032200
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC
Validations
- (5)
Cat. No.
ABIN3032215
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN6242542
Quantity
400 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IF
Validations
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Cat. No.
ABIN3032216
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN6241056
Quantity
400 μL
Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Cat. No.
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Quantity
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Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN6241047
Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN6241054
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
DB
Validations
- (1)
Cat. No.
ABIN6241052
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
DB
Validations
- (1)
Cat. No.
ABIN6241051
Quantity
400 μL
Datasheet
Datasheet
Reactivity
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Application
DB
Validations
- (1)
Cat. No.
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Quantity
400 μL
Datasheet
Datasheet
Latest Publications for our Phosphatase and Tensin Homolog 抗体
: "MiR221 promotes precursor B-cell retention in the bone marrow by amplifying the PI3K-signaling pathway in mice." in: European journal of immunology, Vol. 48, Issue 6, pp. 975-989, (2019) (PubMed).: "Gene expression profiles between cystic and solid vestibular schwannoma indicate susceptible molecules and pathways in the cystic formation of vestibular schwannoma." in: Functional & integrative genomics, Vol. 19, Issue 4, pp. 673-684, (2019) (PubMed).
: "TGF-β induces phosphorylation of phosphatase and tensin homolog: implications for fibrosis of the trabecular meshwork tissue in glaucoma." in: Scientific reports, Vol. 7, Issue 1, pp. 812, (2018) (PubMed).
: "Inhibitors of PARP-1 exert inhibitory effects on the biological characteristics of hepatocellular carcinoma cells in vitro." in: Molecular medicine reports, Vol. 16, Issue 1, pp. 208-214, (2018) (PubMed).
: "Pin1 Promotes Regulated Necrosis Induced by Glutamate in Rat Retinal Neurons via CAST/Calpain2 Pathway." in: Frontiers in cellular neuroscience, Vol. 11, pp. 425, (2018) (PubMed).
: "Bone marrow mesenchymal stem cell-derived exosomal miR-21 protects C-kit+ cardiac stem cells from oxidative injury through the PTEN/PI3K/Akt axis." in: PLoS ONE, Vol. 13, Issue 2, pp. e0191616, (2018) (PubMed).
: "Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated ..." in: Cytokine, Vol. 106, pp. 54-66, (2018) (PubMed).
: "Associations of Functional MicroRNA Binding Site Polymorphisms in IL23/Th17 Inflammatory Pathway Genes with Gastric Cancer Risk." in: Mediators of inflammation, Vol. 2017, pp. 6974696, (2018) (PubMed).
: "VprBP (DCAF1) Regulates RAG1 Expression Independently of Dicer by Mediating RAG1 Degradation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 3, pp. 930-939, (2018) (PubMed).
: "Changes in expression of special AT-rich sequence binding protein 1 and phosphatase and tensin homologue in kidneys of diabetic rats during ageing." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 33, Issue 10, pp. 1734-1741, (2018) (PubMed).
Aliases for Phosphatase and Tensin Homolog 抗体
phosphatase and tensin homolog (PTEN) 抗体phosphatase and tensin homolog (Pten) 抗体
phosphatase and tensin homolog L homeolog (pten.L) 抗体
phosphatase and tensin homolog A (ptena) 抗体
phosphatase and tensin homolog B (ptenb) 抗体
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