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PSMD12 产品

(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. [provided by RefSeq, Jul 2008].

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Featured PSMD12 Categories

PSMD12 抗体

High quality antibodies with extensive validation data.

PSMD12 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PSMD12 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PSMD12 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7246631
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (3)
Cat. No. ABIN6257738
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7142206
Quantity 100 μL
Datasheet Datasheet

Recommended PSMD12 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1773467
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1774691
Quantity 96 tests
Datasheet Datasheet
Reactivity Goat
Analytical Method
Validations
Cat. No. ABIN1749892
Quantity 96 tests
Datasheet Datasheet

Recommended PSMD12 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316625
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316627
Quantity 10 μg
Datasheet Datasheet
Reactivity Saccharomyces cerevisiae
Source Yeast
Validations
Cat. No. ABIN1618817
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PSMD12 Products

Smith, Adle, Zhao, Qin, Kim, Lee: "Endoplasmic Reticulum-associated Degradation of Pca1p, a Polytopic Protein, via Interaction with the Proteasome at the Membrane." in: The Journal of biological chemistry, Vol. 291, Issue 29, pp. 15082-92, (2016) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Isono, Nishihara, Saeki, Yashiroda, Kamata, Ge, Ueda, Kikuchi, Tanaka, Nakano, Toh-e: "The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome." in: Molecular biology of the cell, Vol. 18, Issue 2, pp. 569-80, (2007) (PubMed).

Gandhi, Zhong, Mathivanan, Karthick, Chandrika, Mohan, Sharma, Pinkert, Nagaraju, Periaswamy, Mishra, Nandakumar, Shen, Deshpande, Nayak, Sarker, Boeke, Parmigiani, Schultz, Bader, Pandey: "Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets." in: Nature genetics, Vol. 38, Issue 3, pp. 285-93, (2006) (PubMed).

Listovsky, Oren, Yudkovsky, Mahbubani, Weiss, Lebendiker, Brandeis: "Mammalian Cdh1/Fzr mediates its own degradation." in: The EMBO journal, Vol. 23, Issue 7, pp. 1619-26, (2004) (PubMed).

Bouwmeester, Bauch, Ruffner, Angrand, Bergamini, Croughton, Cruciat, Eberhard, Gagneur, Ghidelli, Hopf, Huhse, Mangano, Michon, Schirle, Schlegl, Schwab, Stein, Bauer, Casari, Drewes, Gavin, Jackson et al.: "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. ..." in: Nature cell biology, Vol. 6, Issue 2, pp. 97-105, (2004) (PubMed).

Finley, Tanaka, Mann, Feldmann, Hochstrasser, Vierstra, Johnston, Hampton, Haber, Mccusker, Silver, Frontali, Thorsness, Varshavsky, Byers, Madura, Reed, Wolf, Jentsch, Sommer, Baumeister, Goldberg et al.: "Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. ..." in: Trends in biochemical sciences, Vol. 23, Issue 7, pp. 244-5, (1998) (PubMed).

Hershko, Ciechanover: "The ubiquitin system." in: Annual review of biochemistry, Vol. 67, pp. 425-79, (1998) (PubMed).

Synonyms and alternative names related to PSMD12

proteasome 26S subunit, non-ATPase 12 (psmd12), proteasome 26S subunit, non-ATPase 12 (PSMD12), proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 (Psmd12), proteasome 26S subunit, non-ATPase 12 (Psmd12), 1500002F15Rik, AI480719, p55, P55, PSMD12, rpn5, Rpn5, wu:fb38a06, wu:fc34f08, wu:fc49f02

Protein level used designations for PSMD12

  • 26S proteasome non-ATPase regulatory subunit 12
  • fc34f08
  • proteasome 26S non-ATPase subunit 12
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
  • 26S proteasome regulatory subunit RPN5
  • 26S proteasome regulatory subunit p55
  • 26S proteasome non-ATPase regulatory subunit 12-like
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