PSMD11 产品
(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012].
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Featured PSMD11 Categories
Recommended PSMD11 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7142202
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6257765
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN202488
Quantity
100 μL
Datasheet
Datasheet
Recommended PSMD11 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6210729
Quantity
96 tests
Datasheet
Datasheet
Recommended PSMD11 蛋白
Latest Publications for our PSMD11 Products
: "Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction." in: The Journal of clinical investigation, Vol. 128, Issue 8, pp. 3630-3641, (2018) (PubMed).: "The Indirubin Derivative 6-Bromoindirubin-3'-Oxime Activates Proteostatic Modules, Reprograms Cellular Bioenergetic Pathways, and Exerts Antiaging Effects." in: Antioxidants & redox signaling, (2017) (PubMed).
: "Inhibition of Proteasome Activity Induces Formation of Alternative Proteasome Complexes." in: The Journal of biological chemistry, Vol. 291, Issue 25, pp. 13147-59, (2016) (PubMed).
: "RPN-6 determines C. elegans longevity under proteotoxic stress conditions." in: Nature, Vol. 489, Issue 7415, pp. 263-8, (2012) (PubMed).
: "Increased proteasome activity in human embryonic stem cells is regulated by PSMD11." in: Nature, Vol. 489, Issue 7415, pp. 304-8, (2012) (PubMed).
: "The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease." in: Nature immunology, Vol. 12, Issue 11, pp. 1063-70, (2011) (PubMed).
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
: "6-bromo-indirubin-3'-oxime (6BIO), a Glycogen synthase kinase-3β inhibitor, activates cytoprotective cellular modules and suppresses cellular senescence-mediated biomolecular damage in human ..." in: Scientific reports, Vol. 7, Issue 1, pp. 11713 (PubMed).
Synonyms and alternative names related to PSMD11
proteasome 26S subunit, non-ATPase 11 (PSMD11), proteasome 26S subunit, non-ATPase 11b (psmd11b), proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 (Psmd11), proteasome 26S subunit, non-ATPase 11 (Psmd11), 1700089D09Rik, 1810019E17Rik, 2610024G20Rik, 2810055C24Rik, C78232, p44.5, P44.5, psmd11, Rpn6, S9, wu:fb55b06, zgc:56580, zgc:77763Protein level used designations for PSMD11
- proteasome 26S non-ATPase subunit 11
- 26S proteasome non-ATPase regulatory subunit 11B
- 26S proteasome regulatory subunit RPN6-B
- proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
- 26S proteasome non-ATPase regulatory subunit 11
- 26S proteasome regulatory subunit 9
- 26S proteasome regulatory subunit RPN6
- 26S proteasome regulatory subunit S9
- 26S proteasome regulatory subunit p44.5
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