PSMC3 产品
(Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. [provided by RefSeq, Jul 2008].
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Featured PSMC3 Categories
Recommended PSMC3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Dog, Human, Monkey, Rat
Application
WB, IHC, IF, IHC (p)
Validations
- (10)
Cat. No.
ABIN1501335
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (7)
Cat. No.
ABIN3022705
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, FACS, ICC
Validations
- (9)
Cat. No.
ABIN5542634
Quantity
100 μL
Datasheet
Datasheet
Recommended PSMC3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316603
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316601
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7414015
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PSMC3 Products
: "Genetic background alters the severity and onset of neuromuscular disease caused by the loss of ubiquitin-specific protease 14 (usp14)." in: PLoS ONE, Vol. 8, Issue 12, pp. e84042, (2013) (PubMed).: "Post-translationally modified S12, absent in transformed breast epithelial cells, is not associated with the 26S proteasome and is induced by proteasome inhibitor." in: International journal of cancer. Journal international du cancer, Vol. 111, Issue 3, pp. 338-47, (2004) (PubMed).
Synonyms and alternative names related to PSMC3
proteasome 26S subunit, ATPase 3 (PSMC3), proteasome (prosome, macropain) 26S subunit, ATPase 3 (Psmc3), proteasome 26S subunit, ATPase 3 (Psmc3), 26S protease regulatory subunit 6A (HCAG_00069), 26S protease regulatory subunit 6A (GL50803_4365), 26S protease regulatory subunit 6A (EDI_316920), 26S protease regulatory subunit 6a (CpipJ_CPIJ006888), 26S protease regulatory subunit 6a (CpipJ_CPIJ006889), 26S protease regulatory subunit 6a (CpipJ_CPIJ010864), 26S protease regulatory subunit 6A (prs6a), proteasome 26S subunit, ATPase 3 (psmc3), 26S protease regulatory subunit 6A-B (LOC100115023), 26S protease regulatory subunit 6A (BBOV_IV004580), 26S protease regulatory subunit 6A, putative (CGB_M2140W), 26S protease regulatory subunit 6A (psmC3), 26S protease regulatory subunit 6A-B (LOC100637883), proteasome 26S subunit, ATPase 3 S homeolog (psmc3.S), nth-like DNA glycosylase 1 S homeolog (nthl1.S), 23.m06430, DDBDRAFT_0186002, DDBDRAFT_0232967, DDB_0186002, DDB_0232967, MGC89608, NV15940, psmc3, PSMC3, psmc3-a, psmc3-b, TBP-1, TBP1, tbp10, wu:fb39a02, zgc:86713Protein level used designations for PSMC3
- 26S protease regulatory subunit 6A
- 26S proteasome AAA-ATPase subunit RPT5
- TBP-1
- Tat-binding protein 1
- human immunodeficiency virus tat transactivator binding protein-1
- proteasome 26S subunit ATPase 3
- proteasome subunit P50
- TAT-binding protein 1
- Tat binding protein 1
- spermatogenic cell/sperm-associated TAT-binding protein homolog SATA
- 26S protease regulatory subunit 6a
- proteasome (prosome, macropain) 26S subunit, ATPase, 3
- proteasome 26S ATPase subunit 3
- 26S protease regulatory subunit 6A-like
- 26S proteasome ATPase 3 subunit
- 26S protease regulatory subunit 6A-B
- 26S proteasome AAA-ATPase subunit RPT5-B
- TAT-binding protein 10
- TBP-10
- proteasome 26S subunit ATPase 3-B
- 26S protease regulatory subunit 6A-A
- 26S proteasome AAA-ATPase subunit RPT5-A
- TAT-binding protein 6
- TBP-6
- proteasome (prosome, macropain) 26S subunit, ATPase 3
- proteasome 26S subunit ATPase 3-A
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