PSMB8 抗体
(Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified\; both isoforms are processed to yield the same mature subunit. [provided by RefSeq, Jul 2008].
recommended
PSMB8 适用: 人 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 1B3 unconjugated
recommended
recommended
PSMB8 抗体 by Grade
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PSMB8 抗体 by 适用
Find PSMB8 抗体 for a variety of species such as anti-Human PSMB8, anti-Mouse PSMB8, anti-Rat PSMB8. The species listed below are among those available. Click on a link to go to the corresponding products.
PSMB8 抗体 by 抗体来源
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PSMB8 抗体 by 克隆形成能力
Find available monoclonal or polyclonal PSMB8 抗体. Click on a link to go to the corresponding products.
PSMB8 抗体 by 克隆
Find PSMB8 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular PSMB8 抗体
Product
Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
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Application
WB, ELISA, IP, IF, IHC (p)
Validations
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
WB, IHC, ELISA, ICC
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Cat. No.
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Quantity
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Datasheet
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Application
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Cat. No.
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Quantity
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Datasheet
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Application
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Cat. No.
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Quantity
100 μL
Datasheet
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Application
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
WB, IHC, IP, ICC
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Cat. No.
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Datasheet
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
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Application
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Cat. No.
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Quantity
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Application
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
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Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
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Cat. No.
ABIN680833
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN680835
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, FACS, IF (cc), IF (p)
Validations
Cat. No.
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Quantity
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Datasheet
Datasheet
Latest Publications for our PSMB8 抗体
: "Predicting and validating the pathway of Wnt3a-driven suppression of osteoclastogenesis." in: Cellular signalling, Vol. 26, Issue 11, pp. 2358-69, (2014) (PubMed).: "Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: implications for Alzheimer's disease." in: Cell death and differentiation, Vol. 18, Issue 6, pp. 1071-81, (2011) (PubMed).
: "PSMB8 (LMP7) but not PSMB9 (LMP2) gene polymorphisms are associated to pigeon breeder's hypersensitivity pneumonitis." in: Respiratory medicine, Vol. 104, Issue 6, pp. 889-94, (2010) (PubMed).
: "Calcium channel blocker verapamil enhances endoplasmic reticulum stress and cell death induced by proteasome inhibition in myeloma cells." in: Neoplasia (New York, N.Y.), Vol. 12, Issue 7, pp. 550-61, (2010) (PubMed).
: "The early marginal zone B cell-initiated T-independent type 2 response resists the proteasome inhibitor bortezomib." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 9, pp. 5637-47, (2010) (PubMed).
: "Single nucleotide polymorphisms in antigen processing machinery component ERAP1 significantly associate with clinical outcome in cervical carcinoma." in: Genes, chromosomes & cancer, Vol. 48, Issue 5, pp. 410-8, (2009) (PubMed).
: "Variation in HLA class I antigen-processing genes and susceptibility to human papillomavirus type 16-associated cervical cancer." in: The Journal of infectious diseases, Vol. 197, Issue 3, pp. 371-81, (2008) (PubMed).
: "Overexpression of the proteasome subunits LMP2, LMP7, and MECL-1, but not PA28 alpha/beta, enhances the presentation of an immunodominant lymphocytic choriomeningitis virus T cell epitope." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 2, pp. 768-78, (2000) (PubMed).
Aliases for PSMB8 抗体
proteasome subunit beta 8 (PSMB8) 抗体proteasome subunit beta 8A (psmb8a) 抗体
proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) (Psmb8) 抗体
proteasome subunit beta 8 (Psmb8) 抗体
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