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PSMB11 产品

(Proteasome (Prosome, Macropain) Subunit, beta Type, 11 (PSMB11))

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Proteasomes generate peptides that are presented by major histocompatibility complex (MHC) I molecules to other cells of the immune system. Proteolysis is conducted by 20S proteasomes, complexes of 28 subunits arranged as a cylinder in 4 heteroheptameric rings: alpha-1 to -7, beta-1 to -7, beta-1 to -7, and alpha-1 to -7. The catalytic subunits are beta-1 (PSMB6; MIM 600307), beta-2 (PSMB7; MIM 604030), and beta-5 (PSMB5; MIM 600306). Three additional subunits, beta-1i (PSMB9; MIM 177045), beta-2i (PSMB10; MIM 176847), and beta-5i (PSMB8; MIM 177046), are induced by gamma-interferon (IFNG; MIM 147570) and are preferentially incorporated into proteasomes to make immunoproteasomes. PSMB11, or beta-5t, is a catalytic subunit expressed exclusively in cortical thymic epithelial cells (Murata et al., 2007

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Synonyms and alternative names related to PSMB11

proteasome subunit beta 11 (PSMB11), proteasome (prosome, macropain) subunit, beta type, 11 (Psmb11), 5830406J20Rik, BETA5T, beta5t

Protein level used designations for PSMB11

  • proteasome subunit beta 5T
  • proteasome subunit beta type-11
  • proteasome subunit beta-5t
  • proteasome beta 11 subunit
  • proteasome subunit beta5t
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