SDF1 beta 蛋白
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- 抗原 See all SDF1 beta (SDF1b) 蛋白
- SDF1 beta (SDF1b) (Stromal Cell Derived Factor 1 beta (SDF1b))
- 生物活性
- Active
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 序列
- KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRL K
- 产品特性
- Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human peripheral blood T-lymphocytes is less than 30 ng/ml, corresponding to a specific activity of >, 3.3 × 104 IU/mg.
- 纯度
- > 97 % by SDS-PAGE and HPLC analyses.
- 内毒素水平
- Level Less than 1EU/µg of rMu SDF-1 beta /CXCL12 as determined by LAL method
- Top Product
- Discover our top product SDF1b 蛋白
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Stromal Cell Derived Factor 1 beta (SDF1b) (Active) protein
SDF1b 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Stromal Cell Derived Factor 1 beta (SDF1b) (Active) proteinSDF1b 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Stromal Cell Derived Factor 1 beta (SDF1b) (AA 22-93) protein (His tag)SDF1b 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Stromal Cell Derived Factor 1 beta (SDF1b) proteinSDF1b 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
- 储存条件
- 4 °C
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- 抗原
- SDF1 beta (SDF1b) (Stromal Cell Derived Factor 1 beta (SDF1b))
- 别名
- SDF-1 beta/cxcl12 (SDF1b 产品)
- 别名
- Pbsf Protein, Scyb12 Protein, Sdf1 Protein, Tlsf Protein, Tpar1 Protein, sdf1a Protein, SDF-1 Protein, chemokine (C-X-C motif) ligand 12 Protein, C-X-C motif chemokine ligand 12 Protein, Cxcl12 Protein, cxcl12 Protein, CXCL12 Protein
- 背景
- SDF-1ª and SDF-1beta, members of the chemokine ª subfamily that lack the ELR domain, were initially identified using the signal sequence trap cloning strategy from a mouse bone-marrow stromal cell line. These proteins were subsequently also cloned from a human stromal cell line as cytokines that supported the proliferation of a stromal cell-dependent pre-B-cell line. SDF-1ª and SDF-1beta cDNAs encode precursor proteins of 89 and 93 amino acid residues, respectively. Both SDF-1ª and SDF-1beta are encoded by a single gene and arise by alternative splicing. The two proteins are identical except for the four amino acid residues that are present in the carboxy-terminus of SDF-1beta and absent from SDF-1ª. SDF-1/PBSF is highly conserved between species, with only one amino acid substitution between the mature human and mouse proteins. SDF-1/PBSF acts via the chemokine receptor CXCR4 and has been shown to be a chemoattractant for T-lymphocytes, monocytes, pro- and pre- B cells, but not neutrophils. Mice lacking SDF-1 or CXCR4 have been found to have impaired B-lymphopoiesis, myelopoiesis, vascular development, cardiogenesis and abnormal neuronal cell migration and patterning in the central nervous system . Synonym: SDF-1 beta/CXCL12, Mouse. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.
- 分子量
- 8.5 kDa, a single non-glycosylated polypeptide chain containing 72 amino acids.
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