Oncostatin M Protein (OSM)
(1 reference)-
- 抗原 See all Oncostatin M (OSM) 蛋白
- Oncostatin M (OSM)
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 序列
- MAAIGSCSKE YRVLLGQLQK QTDLMQDTSR LLDPYIRIQG LDVPKLREHC RERPGAFPSE ETLRGLGRRG FLQTLNATLG CVLHRLADLE QRLPKAQDLE RSGLNIEDLE KLQMARPNIL GLRNNIYCMA QLLDNSDTAE PTKAGRGASQ PPTPTPASDA FQRKLEGCRF LHGYHRFMHS VGRVFSKWGE SPNRSRRHSP HQALRKGVRR TRPSRKGKRL MTRGQLP
- 产品特性
- Fully biologically active when compared to the standard. The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is < 2ng/ml, corresponding to a specific activity of >5.0×105 units/mg.
- 纯度
- > 95 % by SDS-PAGE and HPLC analyses.
- 内毒素水平
- Level Less than 1EU/µg of rHuOSM(227a.a.) as determined by LAL method
- Top Product
- Discover our top product OSM 蛋白
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Oncostatin M (OSM) (AA 26-221) protein (His-Avi Tag)
OSM 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oncostatin M (OSM) (AA 25-206) protein (His tag)OSM 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oncostatin M (OSM) protein (His-Avi Tag,Biotin)OSM 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Oncostatin M (OSM) (AA 26-234) protein (His tag)OSM 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Oncostatin M (OSM) (AA 26-239) protein (His tag)OSM 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Oncostatin M (OSM) (AA 26-221) protein (His tag)OSM 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Oncostatin M (OSM) (AA 1-252) protein (GST tag)OSM 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Oncostatin M (OSM) protein (His tag)OSM 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Oncostatin M (OSM) (AA 26-252) proteinOSM 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20°C. Further dilutions should be made in appropriate buffered solutions.
- 储存条件
- 4 °C
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: "The role of albumin and PPAR-? in differentiation-dependent change of fatty acid profile during differentiation of mesenchymal stem cells to hepatocyte-like cells." in: Cell biochemistry and function, Vol. 32, Issue 5, pp. 410-9, (2014) (PubMed).
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: "The role of albumin and PPAR-? in differentiation-dependent change of fatty acid profile during differentiation of mesenchymal stem cells to hepatocyte-like cells." in: Cell biochemistry and function, Vol. 32, Issue 5, pp. 410-9, (2014) (PubMed).
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- 抗原
- Oncostatin M (OSM)
- 别名
- Oncostatin-M (OSM) (OSM 产品)
- 别名
- OSM Protein, OncoM Protein, oncostatin M Protein, OSM Protein, Osm Protein
- 背景
- Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSH can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells. OSM share several structural and functional characteristics with LIF, IL-6, and CNTF. Human OSM is active on mouse cells. Synonym: Oncostatin-M (OSM)(227a.a.) , Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.
- 分子量
- Approximately 26.0 kDa, a single non-glycosylated polypeptide chain containing 227 amino acids.
- 途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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