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CXCL9 蛋白

CXCL9 宿主: 人 宿主: 大肠杆菌(E. Coli) > 97 % by SDS-PAGE and HPLC analyses. Active
产品编号 ABIN988151
发货至: 中国
  • 抗原 See all CXCL9 蛋白
    CXCL9 (gamma-Interferon-Induced Monokine (CXCL9))
    生物活性
    Active
    宿主
    • 9
    • 4
    • 1
    • 1
    资源
    • 8
    • 3
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    序列
    TPVVRKGRCS CISTNQGTIH LQSLKDLKQF APSPSCEKIE IIATLKNGVQ TCLNPDSADV KELIKKWEKQ VSQKKKQKNG KKHQKKKVLK VRKSQRSRQK KT
    产品特性
    Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human peripheral blood T-lymphocytes is less than 100 ng/ml, corresponding to a specific activity of >, 1.0 × 104 IU/mg.
    纯度
    > 97 % by SDS-PAGE and HPLC analyses.
    内毒素水平
    Level Less than 1EU/µg of rHuMIG/CXCL9 as determined by LAL method
    Top Product
    Discover our top product CXCL9 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
    储存条件
    4 °C
  • 抗原
    CXCL9 (gamma-Interferon-Induced Monokine (CXCL9))
    别名
    MIG/CXCL9 (CXCL9 产品)
    别名
    CMK Protein, Humig Protein, MIG Protein, SCYB9 Protein, crg-10 Protein, BB139920 Protein, Mig Protein, MuMIG Protein, Scyb9 Protein, C-X-C motif chemokine ligand 9 Protein, chemokine (C-X-C motif) ligand 9 Protein, CXCL9 Protein, Cxcl9 Protein
    背景
    CXCL9, a member of the ª subfamily of chemokines that lack the ELR domain, was initially identified as a lymphokine-activated gene in mouse macrophages. The CXCL9 gene is induced in macrophages and in primary glial cells of the central nervous system specifically in response to IFN-γ. CXCL9 has been shown to be a chemoattractant for activated T-lymphocytes and TIL but not for neutrophils or monocytes. The human CXCL9 cDNA encodes a 125 amino acid residue precursor protein with a 22 amino acid residue signal peptide that is cleaved to yield a 103 amino acid residue mature protein. CXCL9 has an extended carboxy-terminus containing greater than 50% basic amino acid residues and is larger than most other chemokines. A chemokine receptor (CXCR3) specific for CXCL9 and IP-10 has recently been cloned and shown to be highly expressed in IL-2-activated T-lymphocytes. Synonym: MIG/CXCL9, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 50mM NaCl.
    分子量
    11.7 kDa, a single non-glycosylated polypeptide chain containing 103 amino acids.
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