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CCL16 蛋白

CCL16 宿主: 人 宿主: 大肠杆菌(E. Coli) > 97 % by SDS-PAGE and HPLC analyses. Active
产品编号 ABIN987914
发货至: 中国
  • 抗原 See all CCL16 蛋白
    CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))
    生物活性
    Active
    宿主
    资源
    • 5
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    序列
    QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNS
    产品特性
    Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human monocytes is less than 100 ng/ml, corresponding to a specific activity of >, 1.0 × 104 IU/mg.
    纯度
    > 97 % by SDS-PAGE and HPLC analyses.
    内毒素水平
    Level Less than 1EU/µg of rHuHCC-4/CCL16 as determined by LAL method
    Top Product
    Discover our top product CCL16 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
    储存条件
    4 °C
  • 抗原
    CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))
    别名
    HCC-4/CCL16 (CCL16 产品)
    别名
    CKb12 Protein, HCC-4 Protein, ILINCK Protein, LCC-1 Protein, LEC Protein, LMC Protein, Mtn-1 Protein, NCC-4 Protein, NCC4 Protein, SCYA16 Protein, SCYL4 Protein, C-C motif chemokine ligand 16 Protein, CCL16 Protein, Ccl16 Protein
    背景
    Human HCC-4, also named NCC-4, liver-expressed chemokine (LEC), and lymphocyte and monocyte chemoattractant (LMC), is a novel CC chemokine identified through bioinformatics. HCC-4 cDNA encodes a 120 amino acid (aa) residue precursor protein with a 23 aa residue predicted signal peptide that is cleaved to generate a 97 aa residue mature protein. HCC-4 is distantly related to other CC chemokines, exhibiting less than 30% sequence identity. Among these CC chemokines, HCC-4 has the most similarity to HCC-1. Two potential polyadenylation signals are present on the human HCC-4 gene, and as a result, two transcripts containing approximately 1,500 base pairs and 500 base pairs have been detected. HCC-4 is expressed weakly by some lymphocytes, including NK cells, T cells, and some T cell clones. The expression of HCC-4 in monocytes is highly upregulated in the presence of IL-10. Synonym: HCC-4/CCL16, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.
    分子量
    11.2 kDa, a single non-glycosylated polypeptide chain containing 97 amino acids.
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