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Epigen 蛋白

EPGN 宿主: 人 宿主: 大肠杆菌(E. Coli) > 98 % by SDS-PAGE and HPLC analyses. Active
产品编号 ABIN987823
发货至: 中国
  • 抗原 See all Epigen (EPGN) 蛋白
    Epigen (EPGN) (Epithelial Mitogen (EPGN))
    生物活性
    Active
    宿主
    • 9
    • 1
    资源
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    序列
    AVTVTPPITA QQADNIEGPI ALKFSHLCLE DHNSYCINGA CAFHHELEKA ICRCFTGYTG ERCEHLTLTS Y
    产品特性
    Determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells. The expected ED50 for this effect is 150-300 ng/ml,corresponding to a specific activity of > 3.3×103 units/mg.
    纯度
    > 98 % by SDS-PAGE and HPLC analyses.
    内毒素水平
    Level Less than 1EU/µg of rHuEPG as determined by LAL method
    Top Product
    Discover our top product EPGN 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
    储存条件
    4 °C
  • 抗原
    Epigen (EPGN) (Epithelial Mitogen (EPGN))
    别名
    Epigen (EPG) (EPGN 产品)
    别名
    ALGV3072 Protein, EPG Protein, PRO9904 Protein, 2310069M11Rik Protein, epigen Protein, RGD1560084 Protein, epithelial mitogen Protein, EPGN Protein, Epgn Protein
    背景
    Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence. Synonym: Epigen (EPG), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.
    分子量
    Approximately 7.9kDa monomeric protein, containing 72 amino acid residues, which comprises the EGF homologous portion of the Epigen precursor.
    途径
    RTK signaling, EGFR Signaling Pathway
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