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EGF Protein (AA 971-1023)

EGF 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS-PAGE analysis. Active
产品编号 ABIN987814
发货至: 中国
  • 抗原 See all EGF 蛋白
    EGF (Epidermal Growth Factor (EGF))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 971-1023
    宿主
    • 20
    • 13
    • 9
    • 4
    • 3
    • 1
    资源
    • 31
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    产品特性
    ED50 <0.6 ng/mL, measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts in serum-free medium and CellTiter-Glo cell viability assay, corresponding to a specific activity of >1.7 x 10^6 units/mg.
    AA 971-1023, expressed with an N-terminal Met
    纯度
    > 95 % by SDS-PAGE analysis.
    内毒素水平
    < 0.1 ng/μg (1 EU/μg) determined by LAL test
    Top Product
    Discover our top product EGF 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against 10 mM PB, pH 7.0.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant human Epidermal Growth Factor (rhEGF) remains stable up to 12 months at -80 °C from date of receipt. Upon reconstitution, rhEGF should be stable up to 4 weeks at 4 °C or up to 6 months at -20 °C.
    有效期
    12 months
  • 抗原
    EGF (Epidermal Growth Factor (EGF))
    别名
    Epidermal Growth Factor (EGF 产品)
    别名
    HOMG4 Protein, URG Protein, AI790464 Protein, CEGF Protein, epidermal growth factor Protein, pro-epidermal growth factor Protein, EGF Protein, egf Protein, CpipJ_CPIJ020278 Protein, Egf Protein
    背景
    Epidermal Growth Factor (EGF) is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-a and VGF (vaccinia virus growth factor). Recombinant human EGF is a 6.2 kDa globular protein containing 53 amino acid residues including 3 intramolecular disulfide-bonds. Recombinant human Epidermal Growth Factor (rhEGF) produced in E. coli is a non-glycosylated polypeptide chain of 54 amino acids. A fully biologically active molecule, rhEGF has a molecular mass of 6.2 kDa analyzed by reducing SDS-PAGE.
    Synonyms: Urogastrone, URG
    分子量
    6.2kDa, observed by reducing SDS-PAGE.
    途径
    NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
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