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CXCL5 Protein (AA 5-78)

CXCL5 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % by SDS-PAGE and HPLC analyses. Active
产品编号 ABIN987804
发货至: 中国
  • 抗原 See all CXCL5 蛋白
    CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 5-78
    宿主
    • 14
    • 8
    • 4
    资源
    • 19
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    序列
    AAVLRELRCV CLQTTQGVHP KMISNLQVFA IGPQCSKVEV VASLKNGKEI CLDPEAPFLK KVIQKILDGG NKE
    产品特性
    Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human peripheral blood neutrophils is less than 10 ng/ml, corresponding to a specific activity of >, 1.0 × 105 IU/mg.
    纯度
    > 97 % by SDS-PAGE and HPLC analyses.
    内毒素水平
    Level Less than 1EU/µg of rHuENA-78/CXCL5 as determined by LAL method
    Top Product
    Discover our top product CXCL5 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
    储存条件
    4 °C
  • 抗原
    CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))
    别名
    ENA-78/CXCL5 (CXCL5 产品)
    别名
    ENA-78 Protein, SCYB5 Protein, Cxcl6 Protein, CXCL5 Protein, GCP-2 Protein, GCP2 Protein, SCYB6 Protein, AMCF-II Protein, LIX Protein, Scyb5 Protein, Scyb6 Protein, C-X-C motif chemokine ligand 5 Protein, C-X-C motif chemokine ligand 6 Protein, chemokine (C-X-C motif) ligand 5 Protein, C-X-C motif chemokine 5 Protein, CXCL5 Protein, Cxcl6 Protein, LOC701946 Protein, LOC703222 Protein, Cxcl5 Protein
    背景
    Epithelial cell-derived neutrophil-activating peptide 78 (ENA-78) is a member of the CXC subfamily of chemokines that has the Glu-Leu-Arg (ELR) motif preceding the CXC motif. Similar to other ELR containing CXC chemokines, ENA-78 is a potent neutrophil chemoattractant and activator. Proteolysis of ENA-78 with cathepsin G and chymotrypsin have yielded N-terminally truncated variants with increased biological activities. ENA-70 and ENA-74 represent truncated recombinant ENA-78 variants missing 8 and 4 aa residues, respectively, from the N-terminus. Recombinant ENA-70 and ENA-74 have been shown to have increased potency in neutrophil chemotaxis and myeloperoxidase and elastase release assays. Synonym: ENA-78/CXCL5 (5-78a.a.), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 50mM NaCl.
    分子量
    8.0 kDa, a single non-glycosylated polypeptide chain containing 74 amino acids.
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity
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