Defensin beta 4 Protein (DEFB4) (AA 33-47)
-
- 抗原 See all Defensin beta 4 (DEFB4) 蛋白
- Defensin beta 4 (DEFB4)
- 生物活性
- Active
- 产品特性
- AA 33-47
-
宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 序列
- EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTK
- 产品特性
- Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay usinghuman monocytes is less than 100 ng/ml, corresponding to a specific activity of >, 1.0 × 104 IU/mg.
- 纯度
- > 98 % by SDS-PAGE and HPLC analyses.
- 内毒素水平
- Level Less than 1EU/µg of rHuBD-4 as determined by LAL method
- Top Product
- Discover our top product DEFB4 蛋白
-
Defensin beta 4 (DEFB4) (AA 23-72) protein (His tag)
DEFB4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Defensin beta 4 (DEFB4) (AA 1-64) protein (GST tag)DEFB4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Defensin beta 4 (DEFB4) (AA 24-64) protein (GST tag)DEFB4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at
- 储存条件
- 4 °C
-
- 抗原
- Defensin beta 4 (DEFB4)
- 别名
- beta-Defensin 4 (BD-4) (DEFB4 产品)
- 别名
- BD-2 Protein, DEFB-2 Protein, DEFB102 Protein, DEFB2 Protein, DEFB4 Protein, HBD-2 Protein, SAP1 Protein, 2310001F05Rik Protein, BD-4 Protein, Defb2 Protein, Defb3 Protein, BNBD-4 Protein, BNBD4 Protein, defensin beta 4A Protein, defensin beta 4 Protein, defensin, beta 4A Protein, DEFB4A Protein, Defb4 Protein
- 背景
- Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The ª-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified, BD-1, BD-2, BD-3 and BD-4. The beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence. beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta-defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues. BD-4 is expressed in testis, stomach, uterus, neutrophils, thyroid, lung and kidney. In addition to its direct antimicrobial activities, BD-4 is chemoattractant towards human blood monocytes. Synonym: beta-Defensin 4 ( BD-4 ), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 130mM NaCl.
- 分子量
- Approximately 6.0 KDa, a single non-glycosylated polypeptide chain containing 50 amino acids.
-
