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Defensin beta 3 Protein (DEFB3)

DEFB3 宿主: 人 宿主: 大肠杆菌(E. Coli) > 98 % by SDS-PAGE and HPLC analyses. Active
产品编号 ABIN987772
发货至: 中国
  • 抗原 See all Defensin beta 3 (DEFB3) 蛋白
    Defensin beta 3 (DEFB3)
    生物活性
    Active
    宿主
    • 4
    • 3
    • 2
    • 1
    资源
    • 6
    • 2
    大肠杆菌(E. Coli)
    序列
    GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRK
    产品特性
    Fully biologically active when compared to standard. The ED50 determined by antimicrobial activity against E.coli. is less than 30000 ng/ml, corresponding to a specific activity of >, 33.3 IU/mg.
    纯度
    > 98 % by SDS-PAGE and HPLC analyses.
    内毒素水平
    Level Less than 1EU/µg of rHuBD-3 as determined by LAL method
    Top Product
    Discover our top product DEFB3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
    储存条件
    4 °C
  • 抗原
    Defensin beta 3 (DEFB3)
    别名
    beta-Defensin 3 (BD-3) (DEFB3 产品)
    别名
    BD-3 Protein, DEFB-3 Protein, DEFB103 Protein, DEFB3 Protein, HBD3 Protein, HBP-3 Protein, HBP3 Protein, hBD-3 Protein, BNBD-3 Protein, BNBD-6 Protein, BNDB-3 Protein, BNDB-6 Protein, BNDB3 Protein, DEFB103A Protein, DEFB2 Protein, DEFB6 Protein, bnbd3 Protein, defb405 Protein, defensin beta 103A Protein, defensin beta 3 Protein, beta-defensin 3 Protein, DEFB103A Protein, Defb3 Protein, DEFB3 Protein
    背景
    Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The ª-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified, BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36 a.a.), a propeptide region. beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta-Defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues. Synonym: beta-Defensin 3 (BD-3), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 130mM NaCl.
    分子量
    Approximately 5.1 KDa, a single non-glycosylated polypeptide chain containing 45 amino acids.
    途径
    Production of Molecular Mediator of Immune Response
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