TWSG1 蛋白
This Recombinant TWSG1 protein is expressed in 大肠杆菌（E. Coli）.
Quick Overview for TWSG1 蛋白 (ABIN935873)
抗原
See all TWSG1 蛋白
TWSG1
(Twisted Gastrulation Homolog 1 (TWSG1))
蛋白类型
Recombinant
生物活性
Active
宿主
人
资源
大肠杆菌（E. Coli）
纯度
> 98 % pure
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序列
- MCNKALCASD VSKCLIQELC QCRPGEGNCS CCKECMLCLG ALWDECCDCV GMCNPRNYSD TPPTSKSTVE ELHEPIPSLF RALTEGDTQL NWNIVSFPVA EELSHHENLV SFLETVNQPH HQNVSVPSNN VHAPYSSDKE HMCTVVYFDD CMSIHQCKIS CESMGASKYR WFHNACCECI GPECIDYGSK TVKCMNCMF
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产品特性
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Purified recombinant Human TSG protein
Expression System: E.coli
Bioactivity: Determined by its ability to neutralize BMP-6 induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED50 for this effect is -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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Twisted Gastrulation Homolog 1 (TWSG1) (AA 1-223) protein (GST tag)
TWSG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Twisted Gastrulation Homolog 1 (TWSG1) protein (His tag)TWSG1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 93 % as determined by SDS-PAGE
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Supplied as a lyophilized powder.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))
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别名
- TSG
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背景
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Twisted Gastrulation Protein (TSG) is a secreted BMP binding protein structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins, and can act either as a BMP4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP4/Chordin complex.
Alternative Names: Twisted Gastrulation Protein protein -
分子量
- 22.2 kDa
抗原
-
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