SOX2 蛋白
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- 抗原 See all SOX2 蛋白
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 序列
- MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY PQHPGLNAHG AAQMQPMHRY DVSALQYNSM TSSQTYMNGS PTYSMSYSQQ GTPGMALGSM GSVVKSEASS SPPVVTSSSH SRAPCQAGDL RDMISMYLPG AEVPEPAAPS RLHMSQHYQS GPVPGTAING TLPLSHM
- 产品特性
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Purified recombinant Human Sox2 protein
Expression System: E.coli - 纯度
- > 95 % pure
- 内毒素水平
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product SOX2 蛋白
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SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-200) protein (His tag)
SOX2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 129-317) protein (His-IF2DI Tag)SOX2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 155-245) protein (GST tag)SOX2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
SRY (Sex Determining Region Y)-Box 2 (SOX2) (AA 1-317) protein (GST tag)SOX2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
SRY (Sex Determining Region Y)-Box 2 (SOX2) protein (Myc-DYKDDDDK Tag)SOX2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Supplied as a lyophilized powder.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- 抗原
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
- 别名
- Sox2 (SOX2 产品)
- 背景
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Sox2, also known as sex determining region Y (SRY)-box 2, belongs to a diverse family of structurally-related transcription factors whose primary structure contains a 79-residue DNA-binding domain, called high mobility group (HMG) box. It plays an essential role in maintaining the pluripotency of embryonic stem cells (ESC) and determination of cell fate. Microarray analysis showed that Sox2 regulates the expression of multiple genes involved in embryonic development including FGF4, YES1 and ZFP206. Sox2 acts as a transcriptional activator after forming a ternary complex with Oct3/4 and a conserved non-coding DNA sequence (CNS1) located approximately 2 kb upstream of the RAX promoter. The introduction of Sox2, Oct4, Myc, and Klf4, into human dermal fibroblasts isolated from a skin biopsy of a healthy research fellow was sufficient to confer a pluripotent state upon the fibroblast genome.
Alternative Names: Sox-2, Sox-2 protein, Sox 2 protein, Sex Determining Region Y- box 2 protein, Sox2, Sox-2 protein, Sox 2 - 分子量
- 34.3 kDa
- 途径
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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