KIT Ligand Protein (KITLG) (full length)
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- 抗原 See all KIT Ligand (KITLG) 蛋白
- KIT Ligand (KITLG)
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- full length
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 产品特性
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Purified recombinant Human SCF protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependant stimulation of Human TF-1 cells is - 纯化方法
- Proprietary chromatographic technique
- 纯度
- > 98 % pure
- Top Product
- Discover our top product KITLG 蛋白
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 说明
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Biological activity: The ED50 as determined by the dose-dependant stimulation of Human TF-1 cells is
- 实验流程
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Protein quantitation was carried out by two independent methods 1. UV spectroscopy at 280 nm using the absorbency value of 0.52 as the extinction coefficient for a 0.1 % (1 mg/mL) solution.
2. Analysis by RP-HPLC, using a standard solution of Stem Cell Factor as a Reference Standard. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute in sterile water not less than 100 μg/mL.
- 缓冲液
- Lyophilized from a concentrated (1 mg/mL) solution in water containing 11 mM CH3COOH.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- 抗原
- KIT Ligand (KITLG)
- 别名
- SCF (KITLG 产品)
- 别名
- Xkl-1 Protein, Xsl Protein, Xsl-1 Protein, Xsl-2 Protein, steel Protein, KITLG Protein, SCF Protein, kitl Protein, kl-1 Protein, mgf Protein, scf Protein, FPH2 Protein, KL-1 Protein, Kitl Protein, MGF Protein, SF Protein, SHEP7 Protein, Clo Protein, Con Protein, Gb Protein, Kitlg Protein, Mgf Protein, SLF Protein, Sl Protein, blz Protein, contrasted Protein, 710-712 Protein, CSF Protein, KITL Protein, KIT ligand L homeolog Protein, KIT ligand Protein, kit ligand Protein, kitlg.L Protein, KITLG Protein, kitlg Protein, Kitl Protein, Kitlg Protein
- 背景
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Stem cell factor / KIT ligand (SCF) is a cytokine which binds CD117(c-Kit). SCF is also known as steel factor or c-kit ligand. SCF exists in two forms, cell surface bound SCF and soluble (or free) SCF. Soluble SCF is produced by the cleavage of surface bound SCF by metalloproteases. SCF is a growth factor important for the survival, proliferation, and differentiation of hematopoietic stem cells and other hematopoietic progenitor cells. One of its roles is to change the BFU-E (burst-forming unit-erythroid) cells, which are the earliest erythrocyte precursors in the erythrocytic series, into the CFU-E (colony-forming unit-erythroid).
Alternative Names: SCF protein, MGF protein, Mast cell growth factor protein, Kitl protein, c-Kit Ligand protein, Steel Factor protein, KL-1 protein, MGF protein, C-kit ligand protein, SF protein, Mast Cell Growth Factor protein, Kit ligand Precursor protein, DKFZp686F2250, Stem Cell Factor protein - 分子量
- 18.409 Da
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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