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cPSA 蛋白

cPSA 宿主: 人 宿主: Human Native > 90 % pure
产品编号 ABIN935720
发货至: 中国
  • 抗原 See all cPSA products
    cPSA (Complexed Prostate Specific Antigen (cPSA))
    蛋白类型
    Native
    宿主
    资源
    • 1
    Human
    产品特性
    Purified native Human PSA/ACT complex protein
    Protein Source: Human plasma and seminal fluid
    纯度
    > 90 % pure
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 缓冲液
    50 mM PBS, pH 7.5, with 0.09 % NaN3.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    -20 °C
    储存方法
    Aliquot and store at -20 °C.
  • 抗原
    cPSA (Complexed Prostate Specific Antigen (cPSA))
    别名
    PSA/ACT complex (cPSA 产品)
    背景
    Prostate Specific Antigen (PSA), a glycoprotein of the glandular kallikrein family, is a serine protease with hymotrypsin-like enzymatic activity, is monitored as increased levels can indicate prostatic neoplasia. PSA released into circulation is present as unbound, free PSA (fPSA) or bound to serum protease inhibitors, such as alpha1-antichymotrypsin (ACT) and alpha2-macroglobulin (A2M). Research indicates that immunoassays for serum levels of PSA alone cannot be relied on to distinguish prostate cancer from benign prostatic hyperplasia (BPH). Serum levels of PSA-ACT complex are reportedly higher in patients with prostate cancer than in those with BPH. As such, measuring the ratio of PSA-ACT to fPSA in patient samples is proving valuable in the differential diagnosis os prostate cancer.
    Description: Human plasma and seminal fluid.
    Alternative Names: Prostate Specific Antigen/1-antichymotrypsin complex antibody, PSA-ACT complex antibody
    分子量
    81 kDa
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