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NOV Protein (full length)

NOV 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % pure Active
产品编号 ABIN935685
发货至: 中国
  • 抗原 See all NOV 蛋白
    NOV (Nephroblastoma Overexpressed (NOV))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    full length
    宿主
    • 5
    • 3
    • 2
    • 1
    • 1
    资源
    • 4
    • 3
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    序列
    MQVAATQRCP PQCPGRCPAT PPTCAPGVRA VLDGCSCCLV CARQRGESCS DLEPCDESSG LYCDRSADPS NQTGICTAVE GDNCVFDGVI YRSGEKFQPS CKFQCTCRDG QIGCVPRCQL DVLLPEPNCP APRKVEVPGE CCEKWICGPD EEDSLGGLTL AAYRPEATLG VEVSDSSVNC IEQTTEWTAC SKSCGMGFST RVTNRNRQCE MLKQTRLCMV RPCEQEPEQP TDKKGKKCLR TKKSLKAIHL QFKNCTSLHT YKPRFCGVCS DGRCCTPHNT KTIQAEFQCS PGQIVKKPVM VIGTCTCHTN CPKNNEAFLQ ELELKTTRGK M
    产品特性
    Purified recombinant Human NOV protein
    Expression System: E.coli
    Bioactivity: Determined by a cell proliferation assay using BALB/c 3T3 cells. The expected ED50 for this effect is 1.0-2.0 µg/mL
    纯度
    > 95 % pure
    内毒素水平
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product NOV 蛋白
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Supplied as a lyophilized powder.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • 抗原
    NOV (Nephroblastoma Overexpressed (NOV))
    别名
    NOV (NOV 产品)
    别名
    CCN3 Protein, IBP-9 Protein, IGFBP-9 Protein, IGFBP9 Protein, NOVh Protein, nov-A Protein, xnov Protein, NovH Protein, C130088N23Rik Protein, nephroblastoma overexpressed Protein, nephroblastoma overexpressed L homeolog Protein, nephroblastoma overexpressed gene Protein, NOV Protein, nov.L Protein, Nov Protein
    背景
    NOV is a member of the CCN family of secreted cysteine rich regulatory proteins. The full length NOV protein contains four structural domains that confer distinct, and sometimes opposing, biological activities. Elevated expression of NOV is associated with certain tumors, including Wilm's tumor and most nephroblastomas. However, in other tumor types and certain cancer cell lines, increased tumorgenicity and proliferation is correlated with decreased NOV expression. Additionally, NOV induces cell adhesion and cell migration by signaling through specific cell surface integrins and by binding to heparin sulfate proteoglycans and to fibulin 1C. NOV has also been reported to exert proangiogenic activities.
    Alternative Names: Nephroblastoma Overexpressed gene protein, CCN3 protein, NovH protein, IGFBP9 protein
    分子量
    36.2 kDa
    途径
    Smooth Muscle Cell Migration, Growth Factor Binding
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