CCL4 蛋白
This Recombinant CCL4 protein is expressed in 大肠杆菌（E. Coli）.
Quick Overview for CCL4 蛋白 (ABIN935657)
抗原
See all CCL4 蛋白
CCL4
(Chemokine (C-C Motif) Ligand 4 (CCL4))
蛋白类型
Recombinant
生物活性
Active
宿主
小鼠
资源
大肠杆菌（E. Coli）
纯度
> 95 % pure
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序列
- APMGSDPPTS CCFSYTSRQL HRSFVMDYYE TSSLCSKPAV VFLTKRGRQI CANPSEPWVT EYMSDLELN
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产品特性
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Purified recombinant Mouse MIP1 beta protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human monocytes using a concentration range of 20.0-100.0 ng/mL. -
内毒素水平
- < 0.1 ng per µg (1 EU/µg).
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Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) (Active) protein
CCL4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant CMA Active
Chemokine (C-C Motif) Ligand 4 (CCL4) (AA 24-92) (Active) protein (Biotin)CCL4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 97 % by SDS PAGE CMA Active
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Supplied as a lyophilized powder.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))
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别名
- MIP1 beta
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背景
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Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ, with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and Mouse MIP-1 alpha and MIP-1 beta are active on human and Mouse hematopoietic cells.
Alternative Names: MIP beta 1 protein, MIP beta-1 protein, MIP1 beta, MIP beta-1, ACT-2 protein, MIP-1 beta protein, CCL4 protein, Macrophage Inflammatory Protein-1 beta protein, MIP beta 1 -
分子量
- 7.8 kDa
抗原
-
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