Purified recombinant Human Myostatin Propeptide protein Expression System: E.coli Bioactivity: Determined by its ability to neutralize the Myostatin inhibitory effect of Mouse MPC-11 cells. The expected ED50 is 0.01-0.04 µg/mL in the presence of 50 ng/mL Myostatin.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
缓冲液
Supplied as a lyophilized powder.
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
抗原
Myostatin Propeptide
背景
Mature Myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin Propeptide exhibits high binding affinity for myostatin and has been shown to be a potent inhibitor of Myostatin. Over-expression of myostatin propeptide in mice resulted in large increases (up to 200 %) in skeletal muscle mass, similar to those observed in Myostatin knockout mice.