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Myostatin Propeptide (Active) 蛋白

宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 98 % pure Active
产品编号 ABIN935653
发货至: 中国
  • 抗原
    Myostatin Propeptide
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    资源
    • 2
    大肠杆菌(E. Coli)
    序列
    MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR
    产品特性
    Purified recombinant Human Myostatin Propeptide protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to neutralize the Myostatin inhibitory effect of Mouse MPC-11 cells. The expected ED50 is 0.01-0.04 µg/mL in the presence of 50 ng/mL Myostatin.
    纯度
    > 98 % pure
    内毒素水平
    < 0.1 ng per µg (1 EU/µg).
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Supplied as a lyophilized powder.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • 抗原
    Myostatin Propeptide
    背景
    Mature Myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin Propeptide exhibits high binding affinity for myostatin and has been shown to be a potent inhibitor of Myostatin. Over-expression of myostatin propeptide in mice resulted in large increases (up to 200 %) in skeletal muscle mass, similar to those observed in Myostatin knockout mice.
    分子量
    27.8 kDa
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