Purified recombinant Human IL17 B protein Expression System: E.coli Bioactivity: Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10ng-100ng. Please Note: Results may vary with PBMC donors.
IL17B is a disulfide-linked homodimer of two 161 amino acid polypeptide chains. It belongs to the IL17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL17A through IL17F, are secreted as homodimers. IL17B is expressed by T-cells and has been shown to stimulate release of TNF-alpha and IL1beta from cells of the monocyte lineage. Alternative Names: NIRF protein, IL20 protein, IL17B, Interleukin 17B protein, ILB-17, ILB-17 protein, ILB 17, IL-17B protein, ILB 17 protein