IGFBP6 蛋白
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- 抗原 See all IGFBP6 蛋白
- IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- Hi-5 Cells
- 序列
- RCPGCGQGVQ AGCPGGCVEE EDGGSPAEGC AEAEGCLRRE GQECGVYTPN CAPGLQCHPP KDDEAPLRAL LLGRGRCLPA RAPAVAEENP KESKPQAGTA RPQDVNRRDQ QRNPGTSTTP SQPNSAGVQD TEMGPCRRHL DSVLQQLQTE VYRGAQTLYV PNCDHRGFYR KRQCRSSQGQ RRGPCWCVDR MGKSLPGSPD GNGSSSCPTG SSG
- 产品特性
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Purified recombinant Human IGF BP6 protein
Expression System: Hi-5 cells
Bioactivity: Determined by its ability to inhibit IGF-II induced proliferation of human MCF-7 cells. The expected ED50 for this effect is 0.1 - 0.4 µg/mL. - 纯度
- > 95 % pure
- 内毒素水平
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product IGFBP6 蛋白
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 说明
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Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Supplied as a lyophilized powder.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- RT/-20 °C
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- 抗原
- IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))
- 别名
- IGF BP6 (IGFBP6 产品)
- 别名
- IBP6 Protein, IGFBP-6 Protein, IGF-BP6 Protein, RBP6A Protein, IGFBP6 Protein, igfbp6 Protein, insulin like growth factor binding protein 6 Protein, insulin-like growth factor binding protein 6 Protein, IGFBP6 Protein, Igfbp6 Protein, IGFBP-6 Protein, igfbp6 Protein
- 背景
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IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP6 is produced by bone cells and is the major IGF-BP present in cerebrospinal fluid, and specifically inhibits IGF-II actions. IGF-BP6 has been shown to inhibit IGF-II-dependent cancers such as neuroblastoma, colon cancer and rhabdomyosarcoma.
Alternative Names: IGF BP-6 protein, IBP-6 protein, IGF BP 6, IGF BP6, IGF BP 6 protein, IGF BP-6 protein, IGF BP-6 - 分子量
- 22.6 kDa
- 途径
- WNT signaling, Myometrial Relaxation and Contraction
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