GDF5 蛋白
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- 抗原 See all GDF5 蛋白
- GDF5 (Growth Differentiation Factor 5 (GDF5))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 序列
- APSATRQGKR PSKNLKARCS RKALHVNFKD MGWDDWIIAP LEYEAFHCEG LCEFPLRSHL EPTNHAVIQT LMNSMDPEST PPTCCVPTRL SPISILFIDS ANNVVYKQYE DMVVESCGCR
- 产品特性
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Purified recombinant Human GDF5 protein
Expression System: E.coli
Bioactivity: Induction of alkaline phosphatase activity in ATDC5 cells: EC50 = 40Nm. - 纯度
- > 98 % pure
- Top Product
- Discover our top product GDF5 蛋白
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 实验流程
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Protein quantitation was carried out by two independent methods1. UV spectroscopy at 280 nm using the absorbency value of 1.15 as the extinction coefficient for a 0.1 % (1 mg/mL) solution.
2. Analysis by RP-HPLC, using a standard solution of GDF5 as a Reference Standard. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Supplied as a lyophilized powder.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- RT/-20 °C
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- 抗原
- GDF5 (Growth Differentiation Factor 5 (GDF5))
- 别名
- GDF5 (GDF5 产品)
- 别名
- CDMP1 Protein, gdf Protein, gdf-5 Protein, GDF5 Protein, BDA1C Protein, BMP14 Protein, LAP4 Protein, OS5 Protein, SYM1B Protein, SYNS2 Protein, Cdmp-1 Protein, bp Protein, brp Protein, Cdmp1 Protein, growth differentiation factor 5 L homeolog Protein, growth differentiation factor 5 Protein, gdf5.L Protein, GDF5 Protein, Gdf5 Protein
- 背景
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GDF-5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type, brachydactyly, type C, and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.
Alternative Names: BMP-14 protein, LAP4 protein, Growth Differentiation Factor 5 protein, GDF 5 protein, GDF-5 protein, Cartilage-derived morphogenetic protein-1 protein, GDF-5 protein, Radotermin protein, CDMP1 protein, GDF5 protein, GDF 5, BMP14 protein, Growth differentiation factor 5 protein, GDF-5 protein, CDMP-1 protein, SYNS2 protein, CDMP1 protein, GDF5, GDF-5 - 分子量
- 26.8 kDa
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