Purified recombinant Mouse CTACK protein Expression System: E.coli Bioactivity: Determined by its ability to chemoattract CXCR3 transfected HEK/293 cells using a concentration range of 10.0-100.0 ng/mL.
CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Both CTACK and CCR10 are expressed in normal and irritated epithelial cells. CTACK selectively attracts CLA+ T-cells and directs them into the skin. CTACK contains the four highly conserved cysteine residues present in most CC chemokines. The mature protein contains 88 amino acid residues. Alternative Names: Cuteaneous T-cell Attracting Chemokine protein, Skinkine protein, ALP protein, CCL27 protein, Eskine protein