CBR1 (Carbonyl reductase 1) is one of several monomeric NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. CBR1 is widely distributed in human tissues. CBR1 metabolizes many toxic environmental quinones and pharmacologically relevant substrates such as the anticancer doxorubicin. CBR1 can also convert prostaglandin E2 to prostaglandin F2-alpha. Recombinant human CBR1 protein was expressed in E. coli and purified by using conventional chromatography. Alternative Names: Carbonyl reductase 1 15 hydroxyprostaglandin dehydrogenase [NADP+] protein, CBR1 protein, CBR 1, Carbonyl reductase [NADPH] 1.CBR 1 protein, CBR protein, hCBR1 protein, SDR21C1 protein, Prostaglandin E(2) 9 reductase., NADPH dependent carbonyl reductase 1 protein, CBR-1, CRN protein, Carbonyl reductase 1 protein, CBR1, Prostaglandin 9 ketoreductase protein, CBR 1 protein, CBR-1 protein