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- 抗原 See all TANK 蛋白
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-119
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV DIASAESSI
- 产品特性
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Purified recombinant Human TANK protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher. - 纯度
- > 90 % pure
- Top Product
- Discover our top product TANK 蛋白
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TRAF Family Member-Associated NFKB Activator (TANK) (AA 1-119) protein (GST tag)
TANK 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
TRAF Family Member-Associated NFKB Activator (TANK) (AA 1-448) protein (His tag)TANK 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
TRAF Family Member-Associated NFKB Activator (TANK) (AA 1-119), (partial) protein (His tag)TANK 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
TRAF Family Member-Associated NFKB Activator (TANK) (AA 1-119), (partial) protein (GST tag)TANK 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
TRAF Family Member-Associated NFKB Activator (TANK) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)TANK 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- TANK protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- RT/-20 °C
- 储存方法
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- 抗原
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
- 别名
- TANK (TANK 产品)
- 别名
- I-TRAF Protein, ITRAF Protein, TRAF2 Protein, C86182 Protein, E430026L09Rik Protein, zgc:153048 Protein, i-traf Protein, tank Protein, traf2 Protein, TRAF family member associated NFKB activator Protein, TRAF family member-associated Nf-kappa B activator Protein, TRAF family member-associated NFKB activator Protein, TRAF family member associated NFKB activator L homeolog Protein, TANK Protein, Tank Protein, tank Protein, tank.L Protein
- 背景
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TANK, also known as TRAF(tumor necrosis factor receptor-associated Factor)-interacting protein, is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby proposing that this protein is an inhibitor of TRAF function that regulates TRAF protein activity by sequestering TRAFs in a latent state in the cytoplasm. Overexpression of TANK inhibits TRAF2-mediated NF-Kappa-B activation signaled by CD40 and both TNF receptors and inhibits LMP1-mediated NF-kappa-B activation by blocking the association of TRAF2 with LMP1. Recombinant human TANK protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: TRAF interacting protein TANK isoform b protein, TRAF interacting protein protein, TRAF family member associated NFKB activator protein, TRAF2 protein, I-TRAF protein, TRAF interacting protein TANK isoform a, ITRAF protein, TRAF family member associated NF KAPPA B activator protein, TRAF interacting protein TANK isoform b I TRAF protein - 分子量
- 13.6 kDa (119 AA)
- 途径
- p53 Pathway, TLR signaling, Activation of Innate immune Response
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