Purified recombinant Human NSE protein Expression System: E.coli Bioactivity: Specific activity: > 8 units/mL. One unit will convert 1.0 m of 2-phosphoglycerate to phospho(enol)pyruvate per minute at pH 7.5 at 25C Molecular weight on SDS-PAGE will appear higher.
纯度
> 95 % pure
内毒素水平
< 1.0 EU per µg of protein (determined by LAL method)
Neuron-specific enolase (NSE) is a glycolytic isoenzyme which is located in central and peripheral neurons and neuroendocrine cells. This enzyme is released into the CSF when neural tissue is injured. Neoplasms derived from neural or neuroendocrine tissue may release NSE into the blood. NSE is a useful substance that has been detected in patients with certain tumors, namely: neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrine tumors, and melanoma. Recombinant NSE was expressed in E. coli and purified by conventional chromatography techniques. Alternative Names: ENO2 protein, Enolase 2 gamma neuronal protein, neuronal) protein, Neuron specific enolase protein, Neuron specific gamma enolase protein, NSE protein, Gamma enolase protein, 2 phospho D glycerate hydrolyase protein, ENOG protein, Neuron-Specific Enolase protein, Eno 2 protein, Neurone specific enolase., Enolase 2 (gamma protein, Neural enolase protein, Enolase2 protein