Human Ubquitin-conjugating enzyme 7 (UbcH7) is a ubiquitin-conjugating enzyme (E2) mediating c-fos degradation, transcription factor NF-kB maturation, and human papilloma virus-mediated p53 and Myc protein degradation, in vitro. The ubiquitin-conjugating enzymes(E2s) are essential components of the post-translational protein ubiquitination pathway, mediating the transfer of activated ubiquitin to substrate proteins. The human UBE2L1-UBE2L4 gene could potentially encode different isoforms of the UbcH7. UBE2L3 gene, located at chromosome 22q11.2, is the only identical family member with introns and encodes a polypeptide sequence identical to that of UbcH7. UbcH7 (154 amino acids) was over-expressed in E. coli and purified by using conventional chromatography techniques. Alternative Names: Ubc7 (Ubiquitin Conjugating enzyme 7) protein, , Ubiquitin-conjugating enzyme E2 G1 protein, Ubiquitin conjugating enzyme E2G 1 (homologous to C protein, EC 6.3.2.19 protein, elegans UBC7) protein, Ubiquitin carrier protein G1 protein, UBE2G1 protein, Ubiquitin-conjugating enzyme E2L 3 UBC 7 protein, UBC7 protein, Ubiquitin conjugating enzyme E2G 1 protein, Ubiquitin protein ligase G1 protein, Ubiquitin conjugating enzyme E2G 1 (UBC7 homolog yeast) protein, Ubiquitin-protein ligase G1 protein, UBE2G protein, UBE 2G protein, Ubiquitin conjugating enzyme E2 G1 protein, E217K protein, Ubiquitin conjugating enzyme E2G 1 (UBC7 homolog C protein, UBC7 homolog yeast protein, elegans) antibody protein