CRYA1 Protein, CTRCT9 Protein, HSPB4 Protein, AI323437 Protein, Acry-1 Protein, Crya-1 Protein, Crya1 Protein, DAcry-1 Protein, lop18 Protein, alpha-a-crystallin Protein, cryaa-A Protein, CRYAA Protein, wu:fc06h04 Protein, zgc:92036 Protein, HspB4 Protein, crystallin alpha A Protein, crystallin, alpha A Protein, alphaA-crystallin Protein, alpha-crystallin A chain-like Protein, crystallin alpha A S homeolog Protein, alpha-crystallin A chain Protein, CRYAA Protein, Cryaa Protein, CpipJ_CPIJ005646 Protein, cryaa Protein, LOC100384978 Protein, cryaa.S Protein, LOC458589 Protein, LOC102724652 Protein
背景
Alpha crystallins are composed of two gene products , alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein(sHSP also known as the HSP20). They act as molecular chaperones and hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits, the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha-crystallins are an autokinase activity and participation in the intracellular architecture. The expression of alpha-A is preferentially restricted to the lens cell. Alternative Names: Alpha-crystallin A chain protein, Crystallin Alpha 1 protein, Acry-1 protein, CRYAA protein, HSPB 4 protein, Crystallin alpha A protein, , HspB4 protein, CRYA 1 protein, Heat shock protein beta 4 protein, Zonular Central Nuclear Cataract protein, Alpha crystallin A chain protein, CRYA1 protein, Heat shock protein beta-4 protein