SNCA
宿主: 人
宿主: 大肠杆菌(E. Coli)
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
应用备注
Alpha synuclein protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
限制
仅限研究用
状态
Lyophilized
溶解方式
Reconstitute in sterile distilled water at a concentration of 1 mg/mL or less.
浓度
1 mg/mL
缓冲液
Lyophilized from a 0.2 µm filtered in 20 mM Tris-HCl buffer, pH 7.5, containing 100 mM NaCl, and 0 mM MgCl2.
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
RT/-20 °C
储存方法
The product is shipped at ambient temperature. Upon receipt, store it immediately at 4 °C in the short term (1 month). For long term storage, aliquot and store at -20 °C or -70 °C.
Alpha-Synuclein, an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Moreover, recent studies have shown that alpha-synuclein has chaperone activity and that this activity is lost upon removing its C-terminal acidic tail (amino acids 96-140). Alternative Names: alphaSYN protein, SNCA protein, Non-A beta component of AD amyloid protein, PARK1 protein, , Non-A4 component of amyloid precursor protein, Synuclein alpha protein, MGC64356 protein, PARK 4 protein, Non-A-beta component of alzheimers disease amyloid protein, MGC127560 protein, Non A beta component of AD amyloid protein, Parkinson disease familial 1 protein, Non A4 component of amyloid precursor protein, alpha-Synuclein protein, MGC110988 protein, NACP protein, Alpha-synuclein isoform NACP140 protein, PD1 protein, precursor of PARK 1 protein, MGC105443 protein, Alpha synuclein protein, PD 1 protein, PARK4 protein