Prothrombin (F2)
(Coagulation Factor II (thrombin) (F2))
蛋白类型
Native
生物活性
Active
宿主
人
资源
Human
产品特性
Purified native Human Prothrombin protein Bioactivity: 9.7 units/mg protein - One unit of activity is equivalent to the Prothrombin activity in one milliliter of human normal plasma. Protein Source: Human serum/plasma
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Liquid
缓冲液
Supplied as a liquid with 50 % Glycerol/H2 O (vol/vol).
注意事项
Donor samples were tested and found to be negative for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Aliquot and store at -20 °C.
抗原
Prothrombin (F2)
(Coagulation Factor II (thrombin) (F2))
Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to gamma-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes. Description: Human serum/plasma.