Purified native Human Factor VII protein Bioactivity: 3296 units/mg protein - Specific activity is determined by the Factor VII clotting assay. One unit of activity is equivalent to the factor VII activity in one milliliter of normal plasma. Protein Source: Human serum/plasma
F7
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
应用备注
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
缓冲液
50 % Glycerol/H2 O (vol/vol).
注意事项
Donor samples were tested and found to be negative for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
Human factor VII is a single chain, vitamin K-dependent, plasma glycoprotein which is synthesized in the liver. Prior to secretion into the blood, post translational modification by a vitamin K-dependent carboxylase produces ten-carboxyglutamic acid (gla) residues located in the NH2-terminal portion of the molecule, which facilitate cell membrane binding. Factor VII is proteolytically activated to the serine protease, factor VIIa, during coagulation. Factor VII can be activated by thrombin, factor IXa, factor Xa or factor XIIa. Description: Human serum/plasma. Alternative Names: Complement Factor VII