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TNFSF15 Protein (Fc Tag)

TNFSF15 宿主: Cynomolgus 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7538575
发货至: 中国
  • 抗原 See all TNFSF15 蛋白
    TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
    蛋白类型
    Recombinant
    宿主
    • 16
    • 9
    • 2
    • 2
    • 1
    Cynomolgus
    资源
    • 12
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Mammalian Cells
    标记
    This TNFSF15 protein is labelled with Fc Tag.
    原理
    Recombinant Cynomolgus TNFSF15 protein with N-terminal human Fc tag
    特异性
    HFc (Glu99-Ala330) TNFSF15 (Leu72-Leu251)
    产品特性
    Extracellular Domain Protein
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product TNFSF15 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
    别名
    TNFSF15 (TNFSF15 产品)
    别名
    TTPAL Protein, TL1 Protein, TL1A Protein, VEGI Protein, VEGI192A Protein, Tl1 Protein, Tl1a Protein, Vegi Protein, tumor necrosis factor superfamily member 15 Protein, TNF superfamily member 15 Protein, tumor necrosis factor (ligand) superfamily, member 15 Protein, TNFSF15 Protein, Tnfsf15 Protein
    背景
    The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
    分子量
    predicted molecular mass of 46.6 kDa after removal of the signal peptide. The apparent molecular mass of hFc-cTNFSF15 is 35-55 kDa due to glycosylation.
    UniProt
    G7PRK8
    途径
    Positive Regulation of Endopeptidase Activity, Autophagy
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