TREM2 Protein (AA 19-171) (Fc Tag)
-
- 抗原 See all TREM2 蛋白
- TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 19-171
-
宿主
- 小鼠
-
资源
- Mammalian Cells
- 标记
- This TREM2 protein is labelled with Fc Tag.
- 原理
- Recombinant mouse TREM2 protein with C-terminal human Fc tag
- 特异性
- Mouse TREM2 (Leu19-Ser171) hFc (Glu99-Ala330)
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product TREM2 蛋白
-
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-174) protein (Fc Tag)
TREM2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) protein (His-Avi Tag,Biotin)TREM2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-174) protein (His tag)TREM2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-174) protein (His tag)TREM2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-171) protein (His tag)TREM2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) protein (Fc Tag)TREM2 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-161) protein (His tag)TREM2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-174) protein (Fc Tag)TREM2 宿主: Cynomolgus 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 1-222) protein (GST tag)TREM2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) (AA 19-174) (Active) protein (His tag)TREM2 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
-
- 抗原
- TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
- 别名
- TREM2 (TREM2 产品)
- 别名
- TREM-A1 Protein, TREM-B1 Protein, TREM2 Protein, trem-2 Protein, trem2a Protein, trem2b Protein, trem2c Protein, TREM-2 Protein, Trem2a Protein, Trem2b Protein, Trem2c Protein, triggering receptor expressed on myeloid cells 2 Protein, trem-like transcript 2 protein Protein, TREM2 Protein, trem2 Protein, LOC100228399 Protein, Trem2 Protein
- 背景
- The protein encoded by this gene is part of the immunoglobulin and lectin-like superfamily and functions as part of the innate immune system. This gene forms part of a cluster of genes on mouse chromosome 17 thought to be involved in innate immunity. This protein associates with the adaptor protein Dap-12 and recruits several factors, such as kinases and phospholipase C-gamma, to form a receptor signaling complex that activates myeloid cells, including dendritic cells and microglia. In humans homozygous loss-of-function mutations in this gene cause Nasu-Hakola disease and mutations in this gene may be risk factors to the development of Alzheimer's disease. In mouse mutations of this gene serve as a pathophysiological model for polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (Nasu-Hakola disease) and for inflammatory bowel disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jan 2013]
- 分子量
- predicted molecular mass of 42.9 kDa after removal of the signal peptide.
- UniProt
- Q99NH8
-
