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- 抗原 See all TM4SF1 蛋白
- TM4SF1 (Transmembrane 4 L Six Family Member 1 (TM4SF1))
- 蛋白类型
- MSP Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human TM4SF1 full length protein membrane nanoparticles (MNPs)
- 产品特性
- Plasma membrane-coated nanoparticles (MNPs) have been used in various applications, including delivery of therapeutic agents and induction of immune responses et al. Unlike the conventional strategies, MNPs directly leverage intact and natural functions of cell membranes, and show high biocompatibility, specificity, and low side effects. Our optimized MNPs platform for the full-length membrane protein production uses membrane coating technology and a HEK293 based expression platform. The high-purity plasma membrane-coated nanoparticles were produced by extrusion after membrane extraction from the host HEK293 cells containing the overexpressed target proteins.
- Top Product
- Discover our top product TM4SF1 蛋白
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Transmembrane 4 L Six Family Member 1 (TM4SF1) (AA 1-202) (Active) protein-VLP
TM4SF1 宿主: 人 宿主: HEK-293 Cells VLP > 95 % as determined by HPLC ELISA, Func, Imm, SPR Active
Transmembrane 4 L Six Family Member 1 (TM4SF1) proteinTM4SF1 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
Transmembrane 4 L Six Family Member 1 (TM4SF1) (AA 1-202) protein (GST tag)TM4SF1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Transmembrane 4 L Six Family Member 1 (TM4SF1) protein (Fc Tag)TM4SF1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- 说明
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Advantages of Membrane Nanoparticles (MNPs):
- High display density of target membrane proteins
- Native structure and orientation of transmembrane protein
- soluble in aqueous solutions for routine biochemical analysis
- Detergent-free purification process
- Strong immunogenicity
- Works for MPs that can´t be produced via VLPs and EXos
- Lack of accurate quantification of the target membrane proteins.
- Need to develop special SPR assayx.
- Cell membranes contain housekeeping proteins that can result in immune response dilution.
- Some membrane proteins can´t be enriched on membrane.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- TM4SF1 (Transmembrane 4 L Six Family Member 1 (TM4SF1))
- 别名
- TM4SF1 (TM4SF1 产品)
- 别名
- MGC85546 Protein, h-l6 Protein, m3s1 Protein, taal6 Protein, H-L6 Protein, L6 Protein, M3S1 Protein, TAAL6 Protein, MM3 Protein, M3s1 Protein, transmembrane 4 L six family member 1 Protein, transmembrane 4 L six family member 1 S homeolog Protein, transmembrane 4 superfamily member 1 Protein, TM4SF1 Protein, tm4sf1.S Protein, tm4sf1 Protein, Tm4sf1 Protein
- 背景
- The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas.
- 分子量
- The human full length TM4SF1 protein has a MW of 21.6 kDa
- UniProt
- P30408
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