TADA2L 蛋白
TADA2A
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all TADA2L (TADA2A) 蛋白
- TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human ADA2A full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Discover our top product TADA2A 蛋白
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Transcriptional Adaptor 2A (TADA2A) (AA 1-305) protein (GST tag)
TADA2A 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Transcriptional Adaptor 2A (TADA2A) protein (His tag)TADA2A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))
- 别名
- ADA2A (TADA2A 产品)
- 别名
- MGC81519 Protein, TADA2A Protein, TADA2L Protein, ADA2 Protein, ADA2A Protein, hADA2 Protein, AV319371 Protein, D030022J10Rik Protein, Tada2l Protein, tada2l Protein, zgc:154057 Protein, transcriptional adaptor 2A L homeolog Protein, transcriptional adaptor 2A Protein, tada2a.L Protein, TADA2A Protein, Tada2a Protein, tada2a Protein
- 背景
- Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. The alpha-2-adrenergic receptors are a type of adrenergic receptors (for adrenaline or epinephrine), which inhibit adenylate cyclase. These receptors include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. They are involved in regulating the release of neurotransmitter molecules from sympathetic nerves and from adrenergic neurons in the central nervous system. The sympathetic nervous system regulates cardiovascular function by activating adrenergic receptors in the heart, blood vessels and kidney. Studies in mouse revealed that both the alpha2A and alpha2C receptor subtypes were required for presynaptic transmitter release from the sympathetic nervous system in the heart and from central noradrenergic neurons. The alpha-2-adrenergic receptors are also involved in catecholamine signaling by extracellular regulated protein kinase 1 and 2 (ERK1/2) pathways. A clear association between the alpha-2-adrenergic receptor and disease has not been yet established. [provided by RefSeq, Sep 2019]
- 分子量
- The human full length ADA2A protein has a MW of 50.6kDa
- UniProt
- P08913
- 途径
- Chromatin Binding
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