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S1PR5 蛋白

S1PR5 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538537
发货至: 中国
  • 抗原 See all S1PR5 蛋白
    S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 3
    • 2
    • 1
    资源
    • 2
    • 2
    • 1
    Mammalian Cells
    原理
    Human S1PR5 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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    Discover our top product S1PR5 蛋白
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))
    别名
    S1PR5 (S1PR5 产品)
    别名
    EDG8 Protein, Edg-8 Protein, S1P5 Protein, SPPR-1 Protein, SPPR-2 Protein, fd11a07 Protein, wu:fd11a07 Protein, zgc:92296 Protein, edg-8 Protein, edg8 Protein, s1p5 Protein, sppr-1 Protein, sppr-2 Protein, xts1p5 Protein, Edg8 Protein, lpB4 Protein, zgc:158362 Protein, sphingosine-1-phosphate receptor 5 Protein, sphingosine-1-phosphate receptor 5a Protein, sphingosine-1-phosphate receptor 5b Protein, S1PR5 Protein, s1pr5a Protein, s1pr5 Protein, S1pr5 Protein, s1pr5b Protein
    背景
    The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1, MIM 601974) are S1P receptors, others (e.g., EDG2, MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008]
    分子量
    The human full length S1PR5 protein has a MW of 41.8kDa
    UniProt
    Q9H228
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