S1PR5 蛋白
S1PR5
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all S1PR5 蛋白
- S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human S1PR5 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Discover our top product S1PR5 蛋白
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Sphingosine-1-Phosphate Receptor 5 (S1PR5) (AA 1-398) protein (GST tag)
S1PR5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))
- 别名
- S1PR5 (S1PR5 产品)
- 别名
- EDG8 Protein, Edg-8 Protein, S1P5 Protein, SPPR-1 Protein, SPPR-2 Protein, fd11a07 Protein, wu:fd11a07 Protein, zgc:92296 Protein, edg-8 Protein, edg8 Protein, s1p5 Protein, sppr-1 Protein, sppr-2 Protein, xts1p5 Protein, Edg8 Protein, lpB4 Protein, zgc:158362 Protein, sphingosine-1-phosphate receptor 5 Protein, sphingosine-1-phosphate receptor 5a Protein, sphingosine-1-phosphate receptor 5b Protein, S1PR5 Protein, s1pr5a Protein, s1pr5 Protein, S1pr5 Protein, s1pr5b Protein
- 背景
- The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1, MIM 601974) are S1P receptors, others (e.g., EDG2, MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008]
- 分子量
- The human full length S1PR5 protein has a MW of 41.8kDa
- UniProt
- Q9H228
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