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S1PR2 蛋白

S1PR2 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538534
发货至: 中国
  • 抗原 See all S1PR2 蛋白
    S1PR2 (Sphingosine-1-Phosphate Receptor 2 (S1PR2))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 2
    • 1
    资源
    • 2
    • 1
    Mammalian Cells
    原理
    Human S1PR2 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    S1PR2 (Sphingosine-1-Phosphate Receptor 2 (S1PR2))
    别名
    S1PR2 (S1PR2 产品)
    别名
    AGR16 Protein, EDG-5 Protein, EDG5 Protein, Gpcr13 Protein, H218 Protein, LPB2 Protein, S1P2 Protein, 1100001A16Rik Protein, Edg5 Protein, LPb2 Protein, GPCR18 Protein, snGPCR18 Protein, sphingosine-1-phosphate receptor 2 Protein, S1PR2 Protein, S1pr2 Protein
    背景
    This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. [provided by RefSeq, Mar 2016]
    分子量
    The human full length S1PR2 protein has a MW of 38.9kDa
    UniProt
    O95136
    途径
    Synaptic Membrane
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