S1PR1 蛋白
S1PR1
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all S1PR1 蛋白
- S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human S1PR1 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Discover our top product S1PR1 蛋白
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Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 1-47) protein (GST tag)
S1PR1 宿主: 人 宿主: 小麦胚 Recombinant WB, AP, AA, ELISA
Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 1-382) protein (GST tag)S1PR1 宿主: 人 宿主: 小麦胚 Recombinant WB, AP, AA, ELISA
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
- 别名
- S1PR1 (S1PR1 产品)
- 别名
- CD363 Protein, CHEDG1 Protein, D1S3362 Protein, ECGF1 Protein, EDG-1 Protein, EDG1 Protein, S1P1 Protein, AI849002 Protein, Edg1 Protein, Lpb1 Protein, S1p Protein, S1p1 Protein, S1P receptor 1 Protein, S1P receptor Edg-1 Protein, edg1 Protein, etID43307.22 Protein, s1p1 Protein, wu:fb98f05 Protein, s1pr1 Protein, xts1p1 Protein, sphingosine-1-phosphate receptor 1 Protein, sphingosine-1-phosphate receptor 1 L homeolog Protein, S1PR1 Protein, S1pr1 Protein, s1pr1 Protein, s1pr1.L Protein
- 背景
- The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
- 分子量
- The human full length S1PR1 protein has a MW of 42.8kDa
- UniProt
- P21453
- 途径
- Signaling Events mediated by VEGFR1 and VEGFR2
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