SMO 蛋白
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- 抗原 See all SMO 蛋白
- SMO (Smoothened Homolog (Drosophila) (SMO))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human SMO full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product SMO 蛋白
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- SMO (Smoothened Homolog (Drosophila) (SMO))
- 别名
- SMO (SMO 产品)
- 别名
- FZD11 Protein, Gx Protein, SMOH Protein, Smoh Protein, E130215L21Rik Protein, bnb Protein, smoothened Protein, XSmo Protein, smoothened, frizzled class receptor Protein, smoothened, frizzled class receptor L homeolog Protein, SMO Protein, Smo Protein, smo.L Protein, smo Protein
- 背景
- The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010]
- 分子量
- The human full length SMO protein has a MW of 86.4kDa
- UniProt
- Q99835
- 途径
- Hedgehog Signaling
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