Serotonin Receptor 4 Protein (HTR4)
HTR4
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all Serotonin Receptor 4 (HTR4) 蛋白
- Serotonin Receptor 4 (HTR4)
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human 5HT4R full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Discover our top product HTR4 蛋白
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Serotonin Receptor 4 (HTR4) (AA 210-264) protein (His-IF2DI Tag)
HTR4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Serotonin Receptor 4 (HTR4) (AA 1-388) protein (GST tag)HTR4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- Serotonin Receptor 4 (HTR4)
- 别名
- 5HT4R (HTR4 产品)
- 别名
- 5-HT4 Protein, 5-HT<4L> Protein, 5HTR4 Protein, 5-HT4S Protein, 5-HT4R Protein, 5 hydroxytryptamine (serotonin) receptor 4 Protein, 5-hydroxytryptamine receptor 4 Protein, Htr4 Protein, HTR4 Protein
- 背景
- This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
- 分子量
- The human full length 5HT4R protein has a MW of 43.8kDa
- UniProt
- Q13639
- 途径
- JAK/STAT Signaling, cAMP Metabolic Process, S100 Proteins
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