Serotonin Receptor 2B Protein (HTR2B)
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- 抗原 See all Serotonin Receptor 2B (HTR2B) 蛋白
- Serotonin Receptor 2B (HTR2B)
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human 5HT2B full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Discover our top product HTR2B 蛋白
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Serotonin Receptor 2B (HTR2B) (AA 1-481) protein (GST tag)
HTR2B 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Serotonin Receptor 2B (HTR2B) (AA 1-56) protein (GST tag)HTR2B 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Serotonin Receptor 2B (HTR2B) (AA 199-359) protein (GST tag)HTR2B 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- Serotonin Receptor 2B (HTR2B)
- 别名
- 5HT2B (HTR2B 产品)
- 别名
- 5-HT2B Protein, 5HT2B Protein, 5htr2b Protein, HTR2B Protein, 5ht2b Protein, zgc:194094 Protein, zgc:194119 Protein, AJ012488 Protein, AV377389 Protein, 5-HT(2B) Protein, 5-hydroxytryptamine receptor 2B Protein, 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled Protein, 5-hydroxytryptamine (serotonin) receptor 2B Protein, HTR2B Protein, htr2b Protein, Htr2b Protein
- 背景
- This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
- 分子量
- The human full length 5HT2B protein has a MW of 54.3kDa
- UniProt
- P41595
- 途径
- JAK/STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
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