Serotonin Receptor 1E Protein (HTR1E)
HTR1E
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all Serotonin Receptor 1E (HTR1E) 蛋白
- Serotonin Receptor 1E (HTR1E)
- 蛋白类型
- Synthetic Nanodisc
- 宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human 5HT1E full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- Discover our top product HTR1E 蛋白
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Serotonin Receptor 1E (HTR1E) (AA 206-276) protein (GST tag)
HTR1E 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- Serotonin Receptor 1E (HTR1E)
- 别名
- 5HT1E (HTR1E 产品)
- 别名
- Htr1ea Protein, HTR1E Protein, 5HT1E Protein, 5-HT1E Protein, 5-HT-1E Protein, 5-hydroxytryptamine (serotonin) receptor 1E Protein, 5-hydroxytryptamine receptor 1E Protein, 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled Protein, Htr1e Protein, HTR1E Protein, htr1e Protein
- 背景
- G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.[UniProtKB/Swiss-Prot Function]
- 分子量
- The human full length 5HT1E protein has a MW of 41.7kDa
- UniProt
- P28566
- 途径
- JAK/STAT Signaling, cAMP Metabolic Process
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