5HT1D 蛋白
HTR1D
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all 5HT1D (HTR1D) 蛋白
- 5HT1D (HTR1D) (Serotonin Receptor 1D (HTR1D))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human 5HT1D full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product HTR1D 蛋白
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Serotonin Receptor 1D (HTR1D) (AA 1-377) protein (GST tag)
HTR1D 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- 5HT1D (HTR1D) (Serotonin Receptor 1D (HTR1D))
- 别名
- 5HT1D (HTR1D 产品)
- 别名
- AI853647 Protein, Gpcr14 Protein, Htr1db Protein, 5-HT1D Protein, HT1DA Protein, HTR1DA Protein, HTRL Protein, RDC4 Protein, 5HT1D Protein, 5-HT-1D Protein, 5-hydroxytryptamine (serotonin) receptor 1D Protein, 5-hydroxytryptamine receptor 1D Protein, Htr1d Protein, HTR1D Protein
- 背景
- G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction.[UniProtKB/Swiss-Prot Function]
- 分子量
- The human full length 5HT1D protein has a MW of 41.9kDa
- UniProt
- P28221
- 途径
- JAK/STAT Signaling
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