5HT1B Receptor 蛋白
HTR1B
宿主: 人
宿主: Mammalian Cells
Synthetic Nanodisc
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- 抗原 See all 5HT1B Receptor (HTR1B) 蛋白
- 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- Mammalian Cells
- 原理
- Human 5HT1B full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product HTR1B 蛋白
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Serotonin Receptor 1B (HTR1B) (AA 1-49) protein (GST tag)
HTR1B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- 5HT1B Receptor (HTR1B) (Serotonin Receptor 1B (HTR1B))
- 别名
- 5HT1B (HTR1B 产品)
- 别名
- 5-HT1B Protein, 5-HT1DB Protein, HTR1D2 Protein, HTR1DB Protein, S12 Protein, 5-HT1Db Protein, 5-HT1-LIKE Protein, HTR1B Protein, 5-HT-dro2B Protein, 5-HT1BDro Protein, 5-HT[1B]Dro Protein, 5-HT[[1BDro]] Protein, 5-HT[[1B]] Protein, 5-HT[[1B]]DRO Protein, 5-HT[[1B]]Dro Protein, 5-HT[[dro2B]] Protein, 5HT-R2B Protein, 5HT-dro2B Protein, 5HT-dro[[2B]] Protein, 5HT1B Protein, 5htdro2b Protein, CG15113 Protein, CG30126 Protein, DRO2B Protein, Dm5HTdro2B Protein, Dmel\\CG15113 Protein, Dmel_CG30126 Protein, d5-HT1B Protein, 5-HT-1B Protein, zgc:194666 Protein, zgc:194690 Protein, 5-hydroxytryptamine receptor 1B Protein, 5-hydroxytryptamine (serotonin) receptor 1B Protein, HTR1B Protein, Htr1b Protein, 5-HT1B Protein, htr1b Protein
- 背景
- The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs. [provided by RefSeq, Nov 2015]
- 分子量
- The human full length 5HT1B protein has a MW of 43.6kDa
- UniProt
- P28222
- 途径
- JAK/STAT Signaling, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, S100 Proteins
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