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Serotonin Receptor 1A Protein (HTR1A)

HTR1A 宿主: 人 宿主: Mammalian Cells Synthetic Nanodisc
产品编号 ABIN7538518
发货至: 中国
  • 抗原 See all Serotonin Receptor 1A (HTR1A) 蛋白
    Serotonin Receptor 1A (HTR1A)
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 6
    • 2
    • 1
    资源
    • 3
    • 2
    • 2
    Mammalian Cells
    原理
    Human 5HT1A full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product HTR1A 蛋白
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    Serotonin Receptor 1A (HTR1A)
    别名
    5HT1A (HTR1A 产品)
    别名
    5-HT-dro2A Protein, 5-HT1ADro Protein, 5-HT[1A]Dro Protein, 5-HT[[1ADro]] Protein, 5-HT[[1A]] Protein, 5-HT[[1A]]DRO Protein, 5HT-R2A Protein, 5HT-dro2A Protein, 5HT-drp[[2A]] Protein, 5HT1A Protein, 5HT[[1ADro]] Protein, 5htdro2a Protein, CG16720 Protein, DRO2A Protein, Dm5HTdro2A Protein, Dmel\\CG16720 Protein, d5-HT1A Protein, 5htr1a Protein, htr1a Protein, HTR1A Protein, Htr1a Protein, 5-Ht1a Protein, Gpcr18 Protein, 5-HT-1A Protein, 5-HT1A Protein, 5HT1a Protein, ADRB2RL1 Protein, ADRBRL1 Protein, G-21 Protein, PFMCD Protein, RAT5HT1A Protein, 5ht1a Protein, adrb2rl1 Protein, adrbrl1 Protein, htr1a-A Protein, 5-hydroxytryptamine (serotonin) receptor 1A Protein, 5-hydroxytryptamine receptor 1A Protein, 5-hydroxytryptamine (serotonin) receptor 1A a Protein, 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled L homeolog Protein, 5-HT1A Protein, HTR1A Protein, htr1aa Protein, Htr1a Protein, htr1a.L Protein
    背景
    This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
    分子量
    The human full length 5HT1A protein has a MW of 46.1kDa
    UniProt
    P08908
    途径
    JAK/STAT Signaling, Synaptic Membrane, Feeding Behaviour
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