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SELPLG Protein (AA 34-356) (His tag)

SELPLG 宿主: Cynomolgus 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7538516
发货至: 中国
  • 抗原 See all SELPLG 蛋白
    SELPLG (Selectin P Ligand (SELPLG))
    蛋白类型
    Recombinant
    产品特性
    AA 34-356
    宿主
    • 6
    • 5
    • 2
    • 1
    Cynomolgus
    资源
    • 6
    • 5
    • 3
    Mammalian Cells
    标记
    This SELPLG protein is labelled with His tag.
    原理
    Recombinant Cynomolgus SELPLG protein with C-terminal 6xHis tag
    特异性
    SELPLG (Leu34-Cys356) 6xHis tag
    产品特性
    Extracellular Domain Protein
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    纯度
    The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product SELPLG 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    SELPLG (Selectin P Ligand (SELPLG))
    别名
    SELPLG (SELPLG 产品)
    别名
    CD162 Protein, CLA Protein, PSGL-1 Protein, PSGL1 Protein, SELPLG Protein, SELPG Protein, Psgl-1 Protein, Psgl1 Protein, Selp1 Protein, Selpl Protein, selectin P ligand Protein, selectin, platelet (p-selectin) ligand Protein, clasper Protein, SELPLG Protein, Selplg Protein, cla Protein
    背景
    This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
    分子量
    predicted molecular mass of 34.3 kDa after removal of the signal peptide.
    UniProt
    A0A7N9CVJ8
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