RAMP1 Protein (AA 27-117) (mFc Tag)
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- 抗原 See all RAMP1 蛋白
- RAMP1 (Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 27-117
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宿主
- 人
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资源
- Mammalian Cells
- 标记
- This RAMP1 protein is labelled with mFc Tag.
- 原理
- Recombinant human RAMP1 Protein with C-terminal mouse Fc tag
- 特异性
- RAMP1 (Cys27-Ser117) mFc (Pro99-Lys330)
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1) (AA 27-117) protein (GST tag)
RAMP1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1) (AA 1-148) protein (GST tag)RAMP1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1) (AA 27-117) protein (His tag)RAMP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % by SDS - PAGE SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- RAMP1 (Receptor (G Protein-Coupled) Activity Modifying Protein 1 (RAMP1))
- 别名
- RAMP1 (RAMP1 产品)
- 别名
- RAMP1 Protein, MGC147096 Protein, 9130218E19Rik Protein, receptor activity modifying protein 1 Protein, receptor (G protein-coupled) activity modifying protein 1 Protein, receptor (calcitonin) activity modifying protein 1 Protein, RAMP1 Protein, ramp1 Protein, Ramp1 Protein
- 背景
- The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
- 分子量
- predicted molecular mass of 36.7 kDa after removal of the signal peptide. The apparent molecular mass of RAMP1-mFc is 35-55 kDa due to glycosylation.
- UniProt
- O60894
- 途径
- cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
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